Evolution of a cycloaddition-rearrangement approach to the squalestatins: a quarter-century odyssey

The highs, lows, and diversions of a journey leading to two syntheses of 6,7-dideoxysqualestatin H5 is described. Both syntheses relied on highly diastereoselective n -alkylations of a tartrate acetonide enolate and subsequent oxidation-hydrolysis to provide an asymmetric entry to β-hydrox...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Almohseni, HAA, Hodgson, DM
التنسيق: Journal article
اللغة:English
منشور في: Thieme Publishing 2020