Evolution of a cycloaddition-rearrangement approach to the squalestatins: a quarter-century odyssey

Evolution of a cycloaddition-rearrangement approach to the squalestatins: a quarter-century odyssey

The highs, lows, and diversions of a journey leading to two syntheses of 6,7-dideoxysqualestatin H5 is described. Both syntheses relied on highly diastereoselective n -alkylations of a tartrate acetonide enolate and subsequent oxidation-hydrolysis to provide an asymmetric entry to β-hydrox...

书目详细资料
Main Authors:	Almohseni, HAA, Hodgson, DM
格式:	Journal article
语言:	English
出版:	Thieme Publishing 2020

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