Innovating cancer drug discovery with refined phenotypic screens

Before molecular pathways in cancer were known to a depth that could predict targets, drug development relied on phenotypic screening, where the effectiveness of candidate chemicals is judged from functional readouts without considering the mechanisms of action. The unraveling of tumor-specific path...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Wang, Z, Hulikova, A, Swietach, P
Format: Journal article
Sprache:English
Veröffentlicht: Cell Press 2024