Innovating cancer drug discovery with refined phenotypic screens

Before molecular pathways in cancer were known to a depth that could predict targets, drug development relied on phenotypic screening, where the effectiveness of candidate chemicals is judged from functional readouts without considering the mechanisms of action. The unraveling of tumor-specific path...

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Bibliographic Details
Main Authors: Wang, Z, Hulikova, A, Swietach, P
Format: Journal article
Language:English
Published: Cell Press 2024