Innovating cancer drug discovery with refined phenotypic screens

Before molecular pathways in cancer were known to a depth that could predict targets, drug development relied on phenotypic screening, where the effectiveness of candidate chemicals is judged from functional readouts without considering the mechanisms of action. The unraveling of tumor-specific path...

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Bibliografske podrobnosti
Main Authors: Wang, Z, Hulikova, A, Swietach, P
Format: Journal article
Jezik:English
Izdano: Cell Press 2024