Amino acid functionalisation using the 2-phosphaethynolate anion. A facile route to (phosphanyl)carbonyl-amino acids

We describe the reactivity of the 2-phosphaethynolate anion (PCO(-)) towards enantiomerically pure α-amino acids (AAs) resulting in the formation of novel salts of phosphinecarboxamides bearing chiral functionalities. These transformations occurred quantitatively with all but one of the amino acids...

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Hlavní autoři: Faria, E, Jupp, A, Goicoechea, J
Médium: Journal article
Jazyk:English
Vydáno: Royal Society of Chemistry 2017