Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow.

Formation of the hematopoietic stem cell (HSC) niche in bone marrow (BM) is tightly associated with endochondral ossification, but little is known about the mechanisms involved. We used the oc/oc mouse, a mouse model with impaired endochondral ossification caused by a loss of osteoclast (OCL) activi...

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Bibliographic Details
Main Authors: Mansour, A, Abou-Ezzi, G, Sitnicka, E, Jacobsen, SE, Wakkach, A, Blin-Wakkach, C
Format: Journal article
Language:English
Published: 2012