Global structural rearrangement of the cell penetrating ribonuclease colicin E3 on interaction with phospholipid membranes.

Nuclease type colicins and related bacteriocins possess the unprecedented ability to translocate an enzymatic polypeptide chain across the Gram-negative cell envelope. Here we use the rRNase domain of the cytotoxic ribonuclease colicin E3 to examine the structural changes on its interaction with the...

Description complète

Détails bibliographiques
Auteurs principaux: Mosbahi, K, Walker, D, James, R, Moore, G, Kleanthous, K
Format: Journal article
Langue:English
Publié: 2006