Myeloproliferative neoplasm stem cells

Myeloproliferative neoplasms (MPNs) arise in the hematopoietic stem cell (HSC) compartment as a result of the acquisition of somatic mutations in a single HSC that provides a selective advantage to mutant HSC over normal HSC and promotes myeloid differentiation to engender a myeloproliferative pheno...

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Bibliographic Details
Main Authors: Mead, A, Mullally, A
Format: Journal article
Published: American Society of Hematology 2017