Myeloproliferative neoplasm stem cells
Myeloproliferative neoplasms (MPNs) arise in the hematopoietic stem cell (HSC) compartment as a result of the acquisition of somatic mutations in a single HSC that provides a selective advantage to mutant HSC over normal HSC and promotes myeloid differentiation to engender a myeloproliferative pheno...
Główni autorzy: | Mead, A, Mullally, A |
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Format: | Journal article |
Wydane: |
American Society of Hematology
2017
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