Impaired antibody affinity maturation process characterizes a subset of patients with common variable immunodeficiency.

Common variable immunodeficiency (CVID) is an heterogeneous syndrome characterized by decreased levels of serum Ig and recurrent bacterial infection. Here, we were interested to study whether a qualitative defect of the affinity Ab maturation process could be combined to the low level of serum Ig in...

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Bibliographic Details
Main Authors: Bonhomme, D, Hammarström, L, Webster, D, Chapel, H, Hermine, O, Le Deist, F, Lepage, E, Romeo, P, Levy, Y
Format: Journal article
Language:English
Published: 2000