Impaired TLR5 functionality is associated with survival in melioidosis.

Impaired TLR5 functionality is associated with survival in melioidosis.

Melioidosis is infection caused by the flagellated saprophyte Burkholderia pseudomallei. TLR5 is a pathogen recognition receptor activated by bacterial flagellin. We studied a genetic variant that encodes a defective TLR5 protein, TLR5(1174C)>T, to elucidate the role of TLR5 in melioidosis. W...

Descripció completa

Dades bibliogràfiques
Autors principals:	West, T, Chantratita, N, Chierakul, W, Limmathurotsakul, D, Wuthiekanun, V, Myers, N, Emond, M, Wurfel, M, Hawn, T, Peacock, S, Skerrett, S
Format:	Journal article
Idioma:	English
Publicat:	2013

Ítems similars

Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis.
per: West, T, et al.
Publicat: (2012)

NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis.
per: T Eoin West, et al.
Publicat: (2014-09-01)

Common TLR1 genetic variation is not associated with death from melioidosis, a common cause of sepsis in rural Thailand
per: Chantratita, N, et al.
Publicat: (2014)

The role of NOD2 in murine and human melioidosis.
per: Myers, N, et al.
Publicat: (2014)

Screen of whole blood responses to flagellin identifies TLR5 variation associated with outcome in melioidosis.
per: Chantratita, N, et al.
Publicat: (2014)

Common TLR1 genetic variation is not associated with death from melioidosis, a common cause of sepsis in rural Thailand.
per: Narisara Chantratita, et al.
Publicat: (2014-01-01)

Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis
per: Wright, S, et al.
Publicat: (2019)

Accuracy of enzyme-linked immunosorbent assay using crude and purified antigens for serodiagnosis of melioidosis.
per: Chantratita, N, et al.
Publicat: (2007)

Intensity of exposure and incidence of melioidosis in Thai children.
per: Cheng, A, et al.
Publicat: (2008)

Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis
per: Shelton W. Wright, et al.
Publicat: (2019-01-01)

A Nonsense Mutation in TLR5 Is Associated with Survival and Reduced IL-10 and TNF-α Levels in Human Melioidosis
per: Chaichana, P, et al.
Publicat: (2017)

Prospective clinical evaluation of the accuracy of 16S rRNA real-time PCR assay for the diagnosis of melioidosis.
per: Chantratita, N, et al.
Publicat: (2007)

Risk factors for recurrent melioidosis in northeast Thailand.
per: Limmathurotsakul, D, et al.
Publicat: (2006)

Role and significance of quantitative urine cultures in diagnosis of melioidosis.
per: Limmathurotsakul, D, et al.
Publicat: (2005)

Pathogenicity of high-dose enteral inoculation of Burkholderia pseudomallei to mice.
per: West, T, et al.
Publicat: (2010)

T-cell responses are associated with survival in acute Melioidosis patients
per: Dunachie, S, et al.
Publicat: (2015)

Recurrent melioidosis in patients in northeast Thailand is frequently due to reinfection rather than relapse.
per: Maharjan, B, et al.
Publicat: (2005)

A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis.
per: Panjaporn Chaichana, et al.
Publicat: (2017-05-01)

Rapid immunofluorescence microscopy for diagnosis of melioidosis.
per: Wuthiekanun, V, et al.
Publicat: (2005)

Role of Burkholderia pseudomallei biofilm formation and lipopolysaccharide in relapse of melioidosis.
per: Limmathurotsakul, D, et al.
Publicat: (2014)

A simple scoring system to differentiate between relapse and re-infection in patients with recurrent melioidosis
per: Limmathurotsakul, D, et al.
Publicat: (2008)

Enzyme-linked immunosorbent assay for the diagnosis of melioidosis: better than we thought.
per: Limmathurotsakul, D, et al.
Publicat: (2011)

Simultaneous infection with more than one strain of Burkholderia pseudomallei is uncommon in human melioidosis.
per: Limmathurotsakul, D, et al.
Publicat: (2007)

Loop-mediated isothermal amplification method targeting the TTS1 gene cluster for detection of Burkholderia pseudomallei and diagnosis of melioidosis.
per: Chantratita, N, et al.
Publicat: (2008)

Antibodies from patients with melioidosis recognize Burkholderia mallei but not Burkholderia thailandensis antigens in the indirect hemagglutination assay.
per: Tiyawisutsri, R, et al.
Publicat: (2005)

Gastrointestinal tract involvement in melioidosis.
per: Teparrukkul, P, et al.
Publicat: (2017)

Short report: Melioidosis in Myanmar: forgotten but not gone?
per: Wuthiekanun, V, et al.
Publicat: (2006)

Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis).
per: Wiersinga, W, et al.
Publicat: (2007)

Dosing regimens of cotrimoxazole (trimethoprim-sulfamethoxazole) for melioidosis.
per: Cheng, A, et al.
Publicat: (2009)

Prospective evaluation of a rapid immunochromogenic cassette test for the diagnosis of melioidosis in northeast Thailand.
per: Cheng, A, et al.
Publicat: (2006)

Rheumatological manifestations in patients with melioidosis.
per: Teparrakkul, P, et al.
Publicat: (2008)

Melioidosis: a clinical overview
per: Limmathurotsakul, D, et al.
Publicat: (2011)

Melioidosis: a clinical overview.
per: Limmathurotsakul, D, et al.
Publicat: (2011)

The role and significance of sputum cultures in the diagnosis of melioidosis.
per: Huis in 't Veld, D, et al.
Publicat: (2005)

T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients.
per: Kemajittra Jenjaroen, et al.
Publicat: (2015-10-01)

Short report: disease severity and outcome of melioidosis in HIV coinfected individuals.
per: Chierakul, W, et al.
Publicat: (2005)

Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis.
per: Koh, G, et al.
Publicat: (2011)

Defining the true sensitivity of culture for the diagnosis of melioidosis using Bayesian latent class models.
per: Limmathurotsakul, D, et al.
Publicat: (2010)

A randomized controlled trial of granulocyte colony-stimulating factor for the treatment of severe sepsis due to melioidosis in Thailand.
per: Cheng, A, et al.
Publicat: (2007)

Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis.
per: Cheng, A, et al.
Publicat: (2008)