OS-9: another piece in the HIF complex story.
In this issue of Molecular Cell, the Semenza group reports that OS-9, a common protein of unassigned function, promotes the O2-dependent degradation of hypoxia inducible factor (HIF) via binding to both HIF and the HIF prolyl-hydroxylases, implying that OS-9 is part of a multiprotein complex involve...
Hlavní autoři: | Flashman, E, McDonough, M, Schofield, C |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2005
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