Context-specific functional effects of IFNGR1 promoter polymorphism.

We report evidence of a polymorphism in the promoter region of IFNGR1 (encoding interferon-gamma receptor 1) that has opposite functional effects in different cellular contexts. It is a deletion/insertion polymorphism that is found in Africans but not Europeans or Asians, and has been associated wit...

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Bibliographic Details
Main Authors: Koch, O, Kwiatkowski, D, Udalova, I
Format: Journal article
Language:English
Published: 2006