Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study

Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study

<p><strong>Background</strong></p> <p>Human prion diseases are rare and usually rapidly fatal neurodegenerative disorders, the most common being sporadic Creutzfeldt-Jakob disease (sCJD). Variants in the PRNP gene that encodes prion protein are strong risk factors for s...

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Main Authors:	Jones, E, Hummerich, H, Viré, E, Uphill, J, Dimitriadis, A, Speedy, H, Campbell, T, Norsworthy, P, Quinn, L, Whitfield, J, Linehan, J, Jaunmuktane, Z, Brandner, S, Jat, P, Nihat, A, How Mok, T, Ahmed, P, Collins, S, Stehmann, C, Sarros, S, Kovacs, GG, Geschwind, MD, Golubjatnikov, A, Frontzek, K, Budka, H, Aguzzi, A, Karamujić-Čomić, H, van der Lee, SJ, Ibrahim-Verbaas, CA, van Duijn, CM, Sikorska, B, Golanska, E, Liberski, PP, Calero, M, Calero, O, Sanchez-Juan, P, Salas, A, Martinón-Torres, F, Bouaziz-Amar, E, Haïk, S, Laplanche, J-L, Brandel, J-P, Amouyel, P, Lambert, J-C, Parchi, P, Bartoletti-Stella, A, Capellari, S, Poleggi, A, Ladogana, A, Pocchiari, M
Format:	Journal article
Language:	English
Published:	Elsevier 2020