PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial

The receptor-binding domain, region II, of the Plasmodium vivax Duffy binding protein (PvDBPII) binds the Duffy antigen on the reticulocyte surface to mediate invasion. A heterologous vaccine challenge trial recently showed that a delayed dosing regimen with recombinant PvDBPII SalI variant formulat...

Full description

Bibliographic Details
Main Authors: Martinez, FJ, White, M, Guillotte-Blisnick, M, Huon, C, Boucharlat, A, Agou, F, England, P, Popovici, J, Hou, MM, Silk, SE, Barrett, JR, Nielsen, CM, Reimer, JM, Mukherjee, P, Chauhan, VS, Minassian, AM, Draper, SJ, Chitnis, CE
Format: Journal article
Language:English
Published: Springer Nature 2024