Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase.
Histone N(ϵ)-methyl lysine demethylases are important in epigenetic regulation. KDM4E (histone lysine demethylase 4E) is a representative member of the large Fe(II)/2-oxoglutarate- dependent family of human histone demethylases. In the present study we report kinetic studies on the reaction of KDM4E...
Prif Awduron: | , , , , , , |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2013
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