Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase.

Histone N(ϵ)-methyl lysine demethylases are important in epigenetic regulation. KDM4E (histone lysine demethylase 4E) is a representative member of the large Fe(II)/2-oxoglutarate- dependent family of human histone demethylases. In the present study we report kinetic studies on the reaction of KDM4E...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Sánchez-Fernández, E, Tarhonskaya, H, Al-Qahtani, K, Hopkinson, R, McCullagh, J, Schofield, C, Flashman, E
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2013