Measurement error, time lag, unmeasured confounding: considerations for longitudinal estimation of the effect of a mediator in randomised clinical trials

Clinical trials are expensive and time-consuming and so should also be used to study how treatments work. This would allow evaluation of theoretical treatment models and refinement and improvement of treatments. Treatment processes can be studied using mediation analysis. Randomised treatment makes...

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Bibliographic Details
Main Authors: Goldsmith, K, Chalder, T, White, P, Sharpe, M
Format: Journal article
Published: SAGE Publications 2016