Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity

Chronic intestinal parasite infection is a major global health problem, but mechanisms that promote chronicity are poorly understood. Here we describe a novel cellular and molecular pathway involved in the development of chronic intestinal parasite infection. We show that, early during development o...

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Bibliographic Details
Main Authors: Worthington, J, Klementowicz, J, Rahman, S, Czajkowska, B, Smedley, C, Waldmann, H, Sparwasser, T, Grencis, R, Travis, M
Format: Journal article
Language:English
Published: Public Library of Science 2013