Demonstrating the utility of the ex vivo murine mycobacterial growth inhibition assay (MGIA) for high-throughput screening of tuberculosis vaccine candidates against multiple Mycobacterium tuberculosis complex strains

<p>Human tuberculosis (TB) is caused by various members of the&nbsp;<em>Mycobacterium tuberculosis</em>&nbsp;(Mtb) complex. Differences in host response to infection have been reported, illustrative of a need to evaluate efficacy of novel vaccine candidates against multiple...

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Bibliographic Details
Main Authors: Painter, H, Willcocks, S, Zelmer, A, Reljic, R, Tanner, R, Fletcher, H
Format: Journal article
Language:English
Published: Elsevier 2024