Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia

There is increasing genetic evidence for the role of microglia in neurodegenerative diseases, including Alzheimer's, Parkinson's, and motor neuron disease. Therefore, there is a need to generate authentic in vitro models to study human microglial physiology. Various methods have been devel...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Washer, SJ, Perez-Alcantara, M, Chen, Y, Steer, J, James, WS, Trynka, G, Bassett, AR, Cowley, SA
Μορφή: Journal article
Γλώσσα:English
Έκδοση: Springer Nature 2022