Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia
There is increasing genetic evidence for the role of microglia in neurodegenerative diseases, including Alzheimer's, Parkinson's, and motor neuron disease. Therefore, there is a need to generate authentic in vitro models to study human microglial physiology. Various methods have been devel...
المؤلفون الرئيسيون: | Washer, SJ, Perez-Alcantara, M, Chen, Y, Steer, J, James, WS, Trynka, G, Bassett, AR, Cowley, SA |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Springer Nature
2022
|
مواد مشابهة
-
Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia
حسب: Sam J. Washer, وآخرون
منشور في: (2022-11-01) -
Honing the double-edged sword: improving human iPSC-microglia models
حسب: Hedegaard, A, وآخرون
منشور في: (2020) -
Variation on a theme: mapping microglial heterogeneity
حسب: Washer, SJ, وآخرون
منشور في: (2021) -
Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
حسب: Vahsen, BF, وآخرون
منشور في: (2022) -
iPSC-derived microglia as a model to study inflammation in idiopathic Parkinson's disease
حسب: Badanjak, K, وآخرون
منشور في: (2021)