Loss of neuronal network resilience precedes seizures and determines the ictogenic nature of interictal synaptic perturbations

The mechanism of seizure emergence and the role of brief interictal epileptiform discharges (IEDs) in seizure generation are two of the most important unresolved issues in modern epilepsy research. We found that the transition to seizure is not a sudden phenomenon, but is instead a slow process that...

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Bibliographic Details
Main Authors: Chang, W-C, Kudlacek, J, Hlinka, J, Chvojka, J, Hadrava, M, Kumpost, V, Powell, AD, Janca, R, Maturana, MI, Karoly, PJ, Freestone, DR, Cook, MJ, Palus, M, Otahal, J, Jefferys, JGR, Jiruska, P
Format: Journal article
Language:English
Published: Springer Nature 2018