Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells.

Modified vaccinia Ankara-expressing Ag85A (MVA85A) is a new tuberculosis (TB) vaccine aimed at enhancing immunity induced by BCG. We investigated the safety and immunogenicity of MVA85A in healthy adolescents and children from a TB endemic region, who received BCG at birth. Twelve adolescents and 24...

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Bibliographic Details
Main Authors:	Scriba, T, Tameris, M, Mansoor, N, Smit, E, van der Merwe, L, Isaacs, F, Keyser, A, Moyo, S, Brittain, N, Lawrie, A, Gelderbloem, S, Veldsman, A, Hatherill, M, Hawkridge, A, Hill, A, Hussey, G, Mahomed, H, Mcshane, H, Hanekom, W
Format:	Journal article
Language:	English
Published:	2010

Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells.

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