Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model

Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model

<p><strong>Background and Purpose:</strong> Fibrosis in kidney allografts is a major post-transplant complication that contributes to graft failure. Lately, multiple potent inhibitors of fibrosis-related pathways have been developed such as galunisertib, an inhibitor of the transfo...

書誌詳細
主要な著者:	van Leeuwen, LL, Ruigrok, MJR, Kessler, BM, Leuvenink, HGD, Olinga, P
フォーマット:	Journal article
言語:	English
出版事項:	Wiley 2023

類似資料

Fibrogenesis imperfecta ossium.
著者:: Carr, A, 等
出版事項: (1995)

Doxycycline alters the porcine renal proteome and degradome during hypothermic machine perfusion
著者:: van Leeuwen, L, 等
出版事項: (2022)

Epithelial-Mesenchymal Transition and its Role in Renal Fibrogenesis
著者:: Brij Mohan Kumar Singh, 等
出版事項: (2022-08-01)

Fibrogenesis in Human Mucosa and Muscularis Precision-Cut Intestinal Slices
著者:: Carin Biel, 等
出版事項: (2024-06-01)

Role of redoximiRs in fibrogenesis
著者:: Marta Fierro-Fernández, 等
出版事項: (2016-04-01)

Reversion of in vivo fibrogenesis by novel chromone scaffoldsReseach in context
著者:: Han-Soo Kim, 等
出版事項: (2019-01-01)

Evaluation of an ex vivo fibrogenesis model using human lung slices prepared from small tissues
著者:: Ying Sun, 等
出版事項: (2023-03-01)

Cardiac fibrogenesis: an immuno-metabolic perspective
著者:: Md Monirul Hoque, 等
出版事項: (2024-03-01)

Intestinal fibrogenesis in inflammatory intestinal disorders
著者:: М.М. Zhaivoronok, 等
出版事項: (2022-12-01)

Are Steatosis and Steatohepatitis Triggers of Hepatic Fibrogenesis?
著者:: Yu.M. Stepanov, 等
出版事項: (2013-04-01)

IL-13 signaling in liver fibrogenesis
著者:: Yan eLiu, 等
出版事項: (2012-05-01)

Expanding the Horizons of Pre-Transplant Renal Vascular Assessment Using Ex Vivo Perfusion
著者:: Carolina Campos Pamplona, 等
出版事項: (2023-06-01)

Endoglina: estructura, funciones biológicas y papel en la fibrogénesis Endoglin: Structure, biological functions, and role in fibrogenesis
著者:: L. García-Pozo, 等
出版事項: (2008-06-01)

Ellagic acid ameliorates renal fibrogenesis by blocking epithelial-to-mesenchymal transition
著者:: Po-Yu Huang, 等
出版事項: (2024-01-01)

The program of renal fibrogenesis is controlled by microRNAs regulating oxidative metabolism
著者:: Verónica Miguel, 等
出版事項: (2021-04-01)

The role of the Notch signaling pathway in liver fibrogenesis.
著者:: E. I. Lebedeva
出版事項: (2020-03-01)

Neutrophils Modulate Fibrogenesis in Chronic Pulmonary Diseases
著者:: Lili Ding, 等
出版事項: (2021-04-01)

Fibrogenesis and carcinoid tumor - a case report
著者:: Eduardo Fonseca Alves Filho, 等
出版事項: (2012-06-01)

Intercellular interactions and their role in fibrogenesis in chronic hepatitis C
著者:: I. A. Karabak, 等
出版事項: (2022-05-01)

TGF-β signaling: critical nexus of fibrogenesis and cancer
著者:: Anna O. Giarratana, 等
出版事項: (2024-06-01)

Emerging advanced approaches for diagnosis and inhibition of liver fibrogenesis
著者:: Tamer A. Addissouky, 等
出版事項: (2024-02-01)

Contribution of intestinal smooth muscle to Crohn's disease fibrogenesis
著者:: C. Severi, 等
出版事項: (2014-10-01)

Inflammation and Fibrogenesis in MAFLD: Role of the Hepatic Immune System
著者:: Pietro Torre, 等
出版事項: (2021-12-01)

Role of Metabolism in Hepatic Stellate Cell Activation and Fibrogenesis
著者:: Wei Hou, 等
出版事項: (2018-11-01)

Protective effects of crude chalaza hydrolysates against liver fibrogenesis via antioxidation, anti-inflammation/anti-fibrogenesis, and apoptosis promotion of damaged hepatocytes
著者:: Yi-Ling Lin, 等
出版事項: (2021-08-01)

Silencing Heat Shock Protein 47 (HSP47) in Fibrogenic Precision-Cut Lung Slices: A Surprising Lack of Effects on Fibrogenesis?
著者:: Mitchel J. R. Ruigrok, 等
出版事項: (2021-02-01)

Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia
著者:: Moreira, LM, 等
出版事項: (2020)

Diagnostic significance of biochemical indicators of liver fibrogenesis in adolescents with obesity
著者:: O. V. Buznytska
出版事項: (2019-02-01)

Is Spheroid a Relevant Model to Address Fibrogenesis in Keloid Research?
著者:: Zélie Dirand, 等
出版事項: (2023-08-01)

Potency of anti-fibrotic herbs on fibrogenesis: A theoretical evaluation
著者:: Ramya Ramadoss, 等
出版事項: (2023-11-01)

Pathophysiological Roles of Ductular Reaction in Liver Inflammation and Hepatic Fibrogenesis
著者:: Keisaku Sato, 等
出版事項: (2023-01-01)

Fibrogenesis in chronic murine colitis is independent of innate lymphoid cells
著者:: Brecht Creyns, 等
出版事項: (2020-09-01)

Cancer driver mutations in endometriosis: Variations on the major theme of fibrogenesis
著者:: Sun‐Wei Guo
出版事項: (2018-10-01)

E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis.
著者:: Daisuke Hasegawa, 等
出版事項: (2010-10-01)

Evaluation of Pirfenidone and Nintedanib in a Human Lung Model of Fibrogenesis
著者:: KM Roach, 等
出版事項: (2021-10-01)

NR4A1 is Involved in Fibrogenesis in Ovarian Endometriosis
著者:: Xinliu Zeng, 等
出版事項: (2018-04-01)

TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice
著者:: Nina D. Thiele, 等
出版事項: (2017-04-01)

Potential Role of the Resident Mesenchymal Stem-Like Cells in Renal Fibrogenesis after Ureteral Obstruction
著者:: Yong-Hua Peng, 等
出版事項: (2019-01-01)

A Metabolic Reprogramming of Glycolysis and Glutamine Metabolism Is a Requisite for Renal Fibrogenesis—Why and How?
著者:: Timothy D. Hewitson, 等
出版事項: (2021-03-01)

PROCOLLAGEN-III PEPTIDE AS AN INDICATOR OF HEPATIC FIBROGENESIS IN PRIMARY SCLEROSING CHOLANGITIS
著者:: Mehal, W, 等
出版事項: (1992)