SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization
Hypoxia is associated with tumor radioresistance; therefore, a predictive marker for tumor hypoxia and a rational target to overcome it have been sought to realize personalized radiotherapy. Here, we show that serine protease inhibitor Kazal type I (SPINK1) meets these 2 criteria. SPINK1 expression...
| Glavni autori: | , , , , , , , , , , |
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| Format: | Journal article |
| Jezik: | English |
| Izdano: |
American Society for Clinical Investigation
2021
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