Comparison of different therapies for neonatal diabetes – glibenclamide vs insulin

Comparison of different therapies for neonatal diabetes – glibenclamide vs insulin

<p>Gain-of-function mutations in the Kir6.2 and SUR subunits of the KATP channel are associated with neonatal diabetes (ND). I used a mouse model selectively expressing the Kir6.2-V59M mutation in pancreatic β-cells (inducible iβ-V59M) to compare the effects of sulphonylurea and insulin therap...

Полное описание

Библиографические подробности
Главный автор:	Iberl, M
Другие авторы:	Ashcroft, F
Формат:	Диссертация
Язык:	English
Опубликовано:	2012
Предметы:	Genetics (life sciences) Medical Sciences Diabetes Physiology and anatomy

Схожие документы

The development of corticothalamic and corticotectal connections in the murine visual system
по: Grant, E
Опубликовано: (2014)

Investigating the role of the fat mass and obesity associated gene (Fto) in obesity
по: McMurray, F
Опубликовано: (2013)

Molecular and behavioural characterisation of novel alpha-synuclein BAC transgenic mouse models of Parkinson's disease
по: Janezic, S
Опубликовано: (2013)

Effects of activating KATP channel mutations on neuronal function
по: McTaggart, J, и др.
Опубликовано: (2011)

Exon skipping peptide-pmos for correction of dystrophin in mouse models of duchenne muscular dystrophy
по: Betts, C, и др.
Опубликовано: (2014)

Analysis of mouse models of insulin secretion disorders
по: Kaizik, S
Опубликовано: (2010)

Utility and limitations of cardiac tissue slices for the study of cardiac electrophysiology
по: Wang, K
Опубликовано: (2015)

Optogenetic analysis of inhibitory circuits in the neocortex
по: Kätzel, D
Опубликовано: (2011)

Timing- and pattern-dependent long-term depression during mouse barrel cortex development
по: Banerjee, A
Опубликовано: (2010)

Comparison of glibenclamide and insulin on neonatal outcomes in pregnant women with gestational diabetes
по: Mitra Behrashi, и др.
Опубликовано: (2016-01-01)

Asymmetry of hippocampal function in mice: left-right differences in memory processing and vulnerability to amyloid beta
по: Shipton, O, и др.
Опубликовано: (2014)

Calcium and chloride dynamics in immature neurons and their role in dendritic growth
по: Wefelmeyer, W
Опубликовано: (2010)

Effects of K-ATP channel mutations on neurological function
по: Lahmann, C
Опубликовано: (2013)

Characterisation of syncoilin
по: Clarke, W
Опубликовано: (2009)

Intracellular chloride and hydrogen ion dynamics in the nervous system
по: Raimondo, J
Опубликовано: (2012)

The effects of a novel substrate on exercise energetics in elite athletes
по: Cox, PJ
Опубликовано: (2013)

Mechanisms of Type 2 diabetes susceptibility
по: Travers, M, и др.
Опубликовано: (2013)

New genetic loci link adipose and insulin biology to body fat distribution
по: Shungin, Dmitry, и др.
Опубликовано: (2015)

The molecular genetics of insulin secretion and signalling
по: McCulloch, L, и др.
Опубликовано: (2011)

Comparative neurotranscriptomics in mammals and birds
по: Belgard, TG
Опубликовано: (2011)

Subplate populations in normal and pathological cortical development
по: Oeschger, F
Опубликовано: (2011)

The biomechanics of turning gait in children with cerebral palsy
по: Dixon, P
Опубликовано: (2015)

Investigating the effects of a point mutation in the TRPC3 channel – cause of cerebellar ataxia in Moonwalker mice – on the Purkinje cells in mice
по: Dulneva, A
Опубликовано: (2012)

Mutations of the same conserved glutamate residue in NBD2 of the sulfonylurea receptor 1 subunit of the KATP channel can result in either hyperinsulinism or neonatal diabetes.
по: Männikkö, R, и др.
Опубликовано: (2011)

Identifying genes in Parkinson’s disease : state of the art
по: Chew, Elaine Guo Yan, и др.
Опубликовано: (2020)

Do malaria parasites mate non-randomly in the mosquito midgut?
Опубликовано: (2000)

The roles of FIAF during skin homeostasis and wound repair in normal and diabetic conditions.
по: Tan, Nguan Soon.
Опубликовано: (2008)

Serotonergic modulation of the claustrum
по: Wong, Kelly Li Lin
Опубликовано: (2022)

An iGlu receptor antagonist and its simultaneous use with an anticancer drug for cancer therapy
по: Luo, Zhong, и др.
Опубликовано: (2015)

Effects of exercise on lipid oxidation at rest: Comparison between high intensity interval exercise and endurance exercise
по: Chen, Raymond Senyuan
Опубликовано: (2016)

A new era for Type 2 diabetes genetics
по: Zeggini, E
Опубликовано: (2007)

A comparison of aquatic and dry land gait characteristics
по: Lim, Cheryl Xue Er.
Опубликовано: (2013)

Dendritic morphology in the medial amygdala of adult male mice is unaffected by testosterone presence
по: Sharma, Loveena
Опубликовано: (2021)

Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment
по: Choong, Cleo Swee Neo, и др.
Опубликовано: (2015)

The developmental and evolutionary roles of isoforms of regulator of G protein signalling 3 in neuronal differentiation
по: Fleenor, S
Опубликовано: (2014)

Differences in meiotic recombination rates in childhood acute lymphoblastic leukemia at an MHC class II hotspot close to disease associated haplotypes
по: Thompson, Pamela, и др.
Опубликовано: (2014)

The clinical and genetic characterisation of young-onset diabetes
по: Mughal, S
Опубликовано: (2014)

Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to Type 2 diabetes
по: Jafar-Mohammadi, B, и др.
Опубликовано: (2009)

Acupuncture in the treatment of finger pulley Injury: a quantitative study
по: Zhao, Chenxi
Опубликовано: (2023)

Effect of acute isotonic beetroot juice supplementation on maximal power in physically active individuals
по: Sim, Rachelle Yahn Yee
Опубликовано: (2022)