Evolutionarily conserved protein sequences of influenza a viruses, avian and human, as vaccine targets.

BACKGROUND: Influenza A viruses generate an extreme genetic diversity through point mutation and gene segment exchange, resulting in many new strains that emerge from the animal reservoirs, among which was the recent highly pathogenic H5N1 virus. This genetic diversity also endows these viruses wit...

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Bibliographic Details
Main Authors: Heiny, A, Miotto, O, Srinivasan, K, Khan, A, Zhang, G, Brusic, V, Tan, T, August, J
Format: Journal article
Language:English
Published: Public Library of Science 2007