Assessing genuine parents-offspring trios for genetic association studies.
OBJECTIVES: Family-based association tests such as the transmission disequilibrium test (TDT) are dependent on the successful ascertainment of true nuclear family trios. Relationship misspecification inevitably occurs in a proportion of trios collected for genotyping which undetected can lead to a l...
Hoofdauteurs: | , , , , , , , |
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Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
2009
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