Imaging the assembly of the Staphylococcal pore-forming toxin alpha-Hemolysin

Alpha-hemolysin is a pore-forming toxin secreted by pathogenic Staphylococcus aureus. Its spontaneous oligomerization and assembly into a trans-bilayer beta-barrel pore is a model for the assembly of many other pore-forming toxins. It is studied here in vitro as a means to probe general membrane pro...

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Bibliographic Details
Main Authors: Thompson, J, James R. Thompson
Other Authors: Wallace, M
Format: Thesis
Language:English
Published: 2009
Subjects: