Clinical Clostridium difficile: clonality and pathogenicity locus diversity.

Clostridium difficile infection (CDI) is an important cause of mortality and morbidity in healthcare settings. The major virulence determinants are large clostridial toxins, toxin A (tcdA) and toxin B (tcdB), encoded within the pathogenicity locus (PaLoc). Isolates vary in pathogenicity from hypervi...

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Bibliographic Details
Main Authors: Dingle, K, Griffiths, D, Didelot, X, Evans, J, Vaughan, A, Kachrimanidou, M, Stoesser, N, Jolley, K, Golubchik, T, Harding, R, Peto, T, Fawley, W, Walker, A, Wilcox, M, Crook, D
Format: Journal article
Language:English
Published: 2011