Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling

Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling

The glucagon-like peptide-1 receptor (GLP1R) is a class B G protein-coupled receptor (GPCR) involved in glucose homeostasis and food intake. GLP1R agonists (GLP1RA) are widely used in the treatment of diabetes and obesity, yet visualizing the endogenous localization, organization and dynamics of a G...

ver descrição completa

Detalhes bibliográficos
Principais autores:	Ast, J, Nasteska, D, Fine, NHF, Nieves, DJ, Koszegi, Z, Lanoiselée, Y, Cuozzo, F, Viloria, K, Bacon, A, Luu, NT, Newsome, PN, Calebiro, D, Owen, DM, Broichhagen, J, Hodson, DJ
Formato:	Journal article
Idioma:	English
Publicado em:	Springer Nature 2023

Registros relacionados

Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling
por: Julia Ast, et al.
Publicado em: (2023-01-01)

Fine-tuned photochromic sulfonylureas for optical control of beta cell Ca2+ fluxes
por: Rückert, A-K, et al.
Publicado em: (2023)

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
por: Julia Ast, et al.
Publicado em: (2020-01-01)

Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
por: Julia Ast, et al.
Publicado em: (2020-10-01)

Detecting Transient Trapping from a Single Trajectory: A Structural Approach
por: Yann Lanoiselée, et al.
Publicado em: (2021-08-01)

GC-globulin/vitamin D-binding protein is required for pancreatic α cell adaptation to metabolic stress
por: Viloria, K, et al.
Publicado em: (2022)

GLP1R and GIPR expression and signaling in pancreatic alpha cells, beta cells and delta cells
por: Shilleh, AH, et al.
Publicado em: (2024)

Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells
por: Xu, W, et al.
Publicado em: (2023)

Vitamin D-binding protein contributes to the maintenance of α cell function 2 and glucagon secretion
por: Viloria, K, et al.
Publicado em: (2020)

Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion
por: Katrina Viloria, et al.
Publicado em: (2020-06-01)

Informing β-cell regeneration strategies using studies of heterogeneity
por: Daniela Nasteska, et al.
Publicado em: (2019-09-01)

Enzyme self-label-bound ATTO700 in single-molecule and super-resolution microscopy
por: Trumpp, M, et al.
Publicado em: (2022)

Hypolipemic action of glucagon in experimental endogenous lipemia in the rat
por: R. Philip Eaton
Publicado em: (1973-05-01)

Time-dependent effects of endogenous hyperglucagonemia on glucose homeostasis and hepatic glucagon action
por: Camila Lubaczeuski, et al.
Publicado em: (2023-06-01)

14-3-3z constrains insulin secretion by regulating mitochondrial function in pancreatic b-cells
por: Mugabo, Y, et al.
Publicado em: (2022)

Glucagon-like peptide-1 receptor regulates thromboxane-induced human platelet activation
por: Cahill, KN, et al.
Publicado em: (2022)

Insulin release: synchronizing beta cells in the pancreas
por: Peercy, BE, et al.
Publicado em: (2024)

Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis.
por: Armstrong, M, et al.
Publicado em: (2015)

Glucagon-Like Peptide-1
por: Joel P. Giblett, BM, BSc, et al.
Publicado em: (2016-06-01)

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology
por: Tom Podewin, et al.
Publicado em: (2018-01-01)

Floral pathway integrator gene expression mediates gradual transmission of environmental and endogenous cues to flowering time
por: Aalt D.J. van Dijk, et al.
Publicado em: (2017-04-01)

Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane
por: Marie-Lise Jobin, et al.
Publicado em: (2023-01-01)

Limited Role of Endogenous Vasopressin/Copeptin in Stimulation of ACTH–Cortisol Secretion during Glucagon Stimulation Test in Humans
por: Katarzyna Malicka, et al.
Publicado em: (2022-11-01)

Liraglutide Activates Glucagon-Like Peptide 1 Receptor to Attenuate Hyperglycemia through Endogenous Beta-Endorphin in Diabetic Rats
por: Kai-Chun Cheng, et al.
Publicado em: (2020-11-01)

An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo
por: Ast, J, et al.
Publicado em: (2022)

Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice
por: Katrine D. Galsgaard, et al.
Publicado em: (2022-12-01)

New insights into the regulation of glucagon secretion by glucagon-like peptide-1.
por: Gromada, J, et al.
Publicado em: (2004)

Evaluation of commercially available glucagon receptor antibodies and glucagon receptor expression
por: Anna Billeschou Bomholt, et al.
Publicado em: (2022-11-01)

Nutritional regulation of hepatic de novo lipogenesis in humans
por: Cross, E, et al.
Publicado em: (2023)

Hepatic fatty acid and glucose handling in metabolic disease: potential impact on cardiovascular disease risk
por: Westcott, F, et al.
Publicado em: (2023)

Glucose in glucagon release.
por: Rorsman, P, et al.
Publicado em: (1990)

Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice
por: Daniela Nasteska, et al.
Publicado em: (2021-08-01)

Beginning of a new era in glucagon research: Breakthrough by the new glucagon assay
por: Dan Kawamori
Publicado em: (2020-09-01)

Endogenous Glucagon-like Peptide-1 Suppresses High-Fat Food Intake by Reducing Synaptic Drive onto Mesolimbic Dopamine Neurons
por: Xue-Feng Wang, et al.
Publicado em: (2015-08-01)

Glucagon Receptor Signaling and Lipid Metabolism
por: Katrine D. Galsgaard, et al.
Publicado em: (2019-04-01)

Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors.
por: Ma, X, et al.
Publicado em: (2005)

Evidence for a lack of inotropic and chronotropic effects of glucagon and glucagon receptors in the human heart
por: Ramón Aranda-Domene, et al.
Publicado em: (2023-05-01)

The effect of endogenously released glucose, insulin, glucagon-like peptide 1, ghrelin on cardiac output, heart rate, stroke volume, and blood pressure
por: Hlebowicz Joanna, et al.
Publicado em: (2011-12-01)

Investigating the Glucagon Receptor and Glucagon-Like Peptide 1 Receptor Activity of Oxyntomodulin-Like Analogues in Male Wistar Rats
por: Samantha L. Price, MRes, et al.
Publicado em: (2015-12-01)

The insulin receptor talks to glucagon?
por: Gromada, J, et al.
Publicado em: (2009)