Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55)
The complement regulatory protein decay accelerating factor (DAF; CD55), inhibits the alternative complement pathway by accelerating decay of the convertase enzymes formed by C3b and factor B. We show, using surface plasmon resonance, that in the absence of Mg2+, DAF binds C3b, factor B, and the Bb...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2005
|