Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55)

The complement regulatory protein decay accelerating factor (DAF; CD55), inhibits the alternative complement pathway by accelerating decay of the convertase enzymes formed by C3b and factor B. We show, using surface plasmon resonance, that in the absence of Mg2+, DAF binds C3b, factor B, and the Bb...

Повний опис

Бібліографічні деталі
Автори: Harris, C, Abbott, R, Smith, R, Morgan, B, Lea, S
Формат: Journal article
Мова:English
Опубліковано: 2005