A quantitative assay of peptide-dependent class I assembly.

We have developed a quantitative assay for the measurement of class I assembly induced by peptide. We have applied this assay to H-2Db, Kb and HLA-A2.1 with a panel of 49 overlapping peptides derived from HIV-1 gag protein. We find that the effects of peptide on assembly form a continuous distributi...

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Bibliographic Details
Main Authors: Elvin, J, Cerundolo, V, Elliott, T, Townsend, A
Format: Journal article
Language:English
Published: 1991