Rolling circle amplification shows a sinusoidal template length-dependent amplification bias.

Biophysical properties of DNA such as its longitudinal and torsional persistence length govern many processes and phenomena in biology, DNA nanotechnology and biotechnology. It has, for example, long been known that the circularization efficiency of short DNA fragments shows a periodic pattern where...

Full description

Bibliographic Details
Main Authors: Joffroy, B, Uca, YO, Prešern, D, Doye, JPK, Schmidt, TL
Format: Journal article
Language:English
Published: Oxford University Press 2017