Cytostatic drug treatment causes seeding of gene promoter methylation

Epigenetic changes in multiple genes are emerging as an important mechanism for tumour cells to acquire resistance to chemotherapy. In the present work, we test the hypothesis that epigenetic organisation in cancer cells can be affected by cytostatic drugs. Colorectal cancer cells were cultured for...

Full description

Bibliographic Details
Main Authors: Bredberg, A, Bodmer, W
Format: Journal article
Language:English
Published: 2007