Critical role of CD28/B7 costimulation in the development of human Th2 cytokine-producing cells.
CD28 is a major costimulatory signal receptor for T cells. We have used human naive CD4+ cells from cord blood to analyze the effect of the CD28/B7 costimulatory pathway on development of T helper (Th) subsets. We show that CD28 costimulation is critical for development of the Th2 cytokine-producing...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
1995
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