The function of Ana1 in centrosome assembly, and the regulation of centriole growth in Drosophila

The function of Ana1 in centrosome assembly, and the regulation of centriole growth in Drosophila

<p>Centrioles are microtubule-based structures that play a crucial role in the formation of centrosomes, cilia and flagella. Centriole defects are linked to several human diseases such as microcephaly, primordial dwarfism, cancer and ciliopathies. In Drosophila, Plk4, Sas-6, Ana2, Sas-4 and As...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Saurya, S
Awduron Eraill:	Raff, J
Fformat:	Traethawd Ymchwil
Cyhoeddwyd:	2018

Eitemau Tebyg

Drosophila Ana1 is required for centrosome assembly and centriole elongation
gan: Saurya, S, et al.
Cyhoeddwyd: (2016)

Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation
gan: Alvarez-Rodrigo, I, et al.
Cyhoeddwyd: (2021)

Drosophila Sas-6, Ana2 and Sas-4 self-organise into macromolecular structures that can be used to probe centriole and centrosome assembly
gan: Gartenmann, L, et al.
Cyhoeddwyd: (2020)

Examining molecular interactions and dynamics in centrosome and centriole assembly
gan: Gartenmann, L
Cyhoeddwyd: (2018)

CP110 exhibits novel regulatory activities during centriole assembly in Drosophila.
gan: Franz, A, et al.
Cyhoeddwyd: (2013)

SAPs as a new model to probe the pathway of centriole and centrosome assembly
gan: Wainman, A
Cyhoeddwyd: (2021)

Drosophila PLP assembles centriolar-clouds that promote centriole stability, cohesion and MT nucleation
gan: Roque, H, et al.
Cyhoeddwyd: (2018)

Drosophila PLP assembles pericentriolar clouds that promote centriole stability, cohesion and MT nucleation
gan: Roque, H, et al.
Cyhoeddwyd: (2018)

Centrioles, centrosomes, and cilia in health and disease.
gan: Nigg, E, et al.
Cyhoeddwyd: (2009)

Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes
gan: Wong, S-S, et al.
Cyhoeddwyd: (2025)

Drosophila PLP assembles pericentriolar clouds that promote centriole stability, cohesion and MT nucleation.
gan: Helio Roque, et al.
Cyhoeddwyd: (2018-02-01)

A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila
gan: Dobbelaere, J, et al.
Cyhoeddwyd: (2008)

A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.
gan: Jeroen Dobbelaere, et al.
Cyhoeddwyd: (2008-09-01)

Drosophila Ana2 is a conserved centriole duplication factor.
gan: Stevens, N, et al.
Cyhoeddwyd: (2010)

Cdk1 phosphorylates Drosophila Sas-4 to recruit Polo to daughter centrioles and convert them to centrosomes
gan: Raff, J, et al.
Cyhoeddwyd: (2016)

Separate To Operate: the Centriole-Free Inner Core of the Centrosome Regulates the Assembly of the Intranuclear Spindle in Toxoplasma gondii
gan: Ramiro Tomasina, et al.
Cyhoeddwyd: (2022-10-01)

Centrioles regulate centrosome size by controlling the rate of Cnn incorporation into the PCM.
gan: Conduit, P, et al.
Cyhoeddwyd: (2010)

Cnn dynamics drive centrosome size asymmetry to ensure daughter centriole retention in Drosophila neuroblasts.
gan: Conduit, P, et al.
Cyhoeddwyd: (2010)

Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly
gan: Wong, S-S, et al.
Cyhoeddwyd: (2022)

Evolutionary conservation of centriole rotational asymmetry in the human centrosome
gan: Noémie Gaudin, et al.
Cyhoeddwyd: (2022-03-01)

Stabilization of Cartwheel-less Centrioles for Duplication Requires CEP295-Mediated Centriole-to-Centrosome Conversion
gan: Denisse Izquierdo, et al.
Cyhoeddwyd: (2014-08-01)

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication
gan: Andrew Kodani, et al.
Cyhoeddwyd: (2015-08-01)

CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion
gan: Enrico S. Atorino, et al.
Cyhoeddwyd: (2020-02-01)

Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay
gan: Menuka Karki, et al.
Cyhoeddwyd: (2017-06-01)

Stable centrosomal roots disentangle to allow interphase centriole independence.
gan: Robert Mahen
Cyhoeddwyd: (2018-04-01)

Dynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors
gan: Olivier Mercey, et al.
Cyhoeddwyd: (2019-09-01)

Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68
gan: Ning Huang, et al.
Cyhoeddwyd: (2017-04-01)

cNap1 bridges centriole contact sites to maintain centrosome cohesion.
gan: Robert Mahen
Cyhoeddwyd: (2022-10-01)

cNap1 bridges centriole contact sites to maintain centrosome cohesion
gan: Robert Mahen
Cyhoeddwyd: (2022-10-01)

The dynamics of centrosome assembly in the early Drosophila embryo
gan: Wong, SS
Cyhoeddwyd: (2021)

NANOG/NANOGP8 Localizes at the Centrosome and is Spatiotemporally Associated with Centriole Maturation
gan: Erika Mikulenkova, et al.
Cyhoeddwyd: (2020-03-01)

A molecular mechanism of mitotic centrosome assembly in Drosophila
gan: Conduit, PT, et al.
Cyhoeddwyd: (2014)

A molecular mechanism of mitotic centrosome assembly in Drosophila
gan: Paul T Conduit, et al.
Cyhoeddwyd: (2014-08-01)

PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN
gan: Andrew Michael Sydor, et al.
Cyhoeddwyd: (2018-08-01)

The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies.
gan: Cottee, M, et al.
Cyhoeddwyd: (2015)

The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies
gan: Matthew A Cottee, et al.
Cyhoeddwyd: (2015-05-01)

Centriole distal-end proteins CP110 and Cep97 influence centriole cartwheel growth at the proximal end
gan: Aydogan, MG, et al.
Cyhoeddwyd: (2022)

Daughter centrioles assemble preferentially towards the nuclear envelope in Drosophila syncytial embryos
gan: Neil H. J. Cunningham, et al.
Cyhoeddwyd: (2022-01-01)

Drosophila Spd-2 recruits PCM to the sperm centriole, but is dispensable for centriole duplication.
gan: Dix, C, et al.
Cyhoeddwyd: (2007)

Building the Drosophila centriole: a structural investigation of the centriolar Proteins SAS-6, SAS-4 and Ana2
gan: Cottee, M
Cyhoeddwyd: (2014)