Chemo-enzymatic synthesis of bicyclic gamma-lactams using clavaminic acid synthase
Incubation of the γ-lactam analogue of proclavaminic acid, (±)-threo-5-amino-3-hydroxy-2-(1'-aza-2'-oxocyclopentyl) acid, led to production of two bicyclic γ-lactam products.
| Autori principali: | , , , , , , , |
|---|---|
| Natura: | Journal article |
| Pubblicazione: |
1997
|