Synthesis of 3-chloro-2-formylpyrrole derivatives

Regioselective deprotonation of 3-chloro-1-tosylpyrrole is used to prepare the 2-formyl derivative. Application of this chemistry in a synthesis of the left hand pyrrolo-furan substructure of roseophilin is described.

Bibliographic Details
Main Authors: Robertson, J, Kuhnert, N, Zhao, Y
Format: Journal article
Language:English
Published: 2000