Protein inhibitor of NOS1 plays a central role in the regulation of NOS1 activity in human dilated hearts

Protein inhibitor of NOS1 plays a central role in the regulation of NOS1 activity in human dilated hearts

An essential factor for the production of nitric oxide by nitric oxide synthase 1 (NOS1), major modulator of cardiac function, is the cofactor tetrahydrobiopterin (BH4). BH4 is regulated by GTP cyclohydrolase 1, the rate-limiting enzyme in BH4 biosynthesis which catalyses the formation of dihydroneo...

Bibliográfalaš dieđut
Váldodahkkit:	Roselló-Lletí, E, Tarazón, E, Ortega, A, Gil-Cayuela, C, Carnicer, R, Lago, F, González-Juanatey, J, Portolés, M, Rivera, M
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	Nature Publishing Group 2016

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