Regulation of the base excision repair pathway

<p>Maintenance of genomic stability is paramount for survival of an organism; failure to repair DNA damage ultimately leads to the accumulation of genetically unstable cells and the onset of different human diseases including cancer. DNA single strand breaks and base oxidation/alkylation are a...

Full description

Bibliographic Details
Main Authors: Fletcher, S, Poletto, M
Other Authors: Dianov, G
Format: Thesis
Language:English
Published: 2017
Subjects: