Strategy for monitoring T cell responses to NY-ESO-1 in patients with any HLA class I allele.

NY-ESO-1 elicits frequent antibody responses in cancer patients, accompanied by strong CD8(+) T cell responses against HLA-A2-restricted epitopes. To broaden the range of cancer patients who can be assessed for immunity to NY-ESO-1, a general method was devised to detect T cell reactivity independen...

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Bibliographic Details
Main Authors: Gnjatic, S, Nagata, Y, Jager, E, Stockert, E, Shankara, S, Roberts, B, Mazzara, G, Lee, S, Dunbar, P, Dupont, B, Cerundolo, V, Ritter, G, Chen, Y, Knuth, A, Old, L
Format: Journal article
Language:English
Published: 2000