Effect of cell density on the rate of glycosaminoglycan accumulation by disc and cartilage cells in vitro.

Aggrecan concentration falls markedly during cartilage and disc degeneration with unfortunate biomechanical and physiological consequences. There is thus now an increasing interest in developing biological methods for its replacement. One approach is to stimulate aggrecan and hence glycosaminoglycan...

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Bibliographic Details
Main Authors: Kobayashi, S, Meir, A, Urban, J
Format: Journal article
Language:English
Published: 2008