Biochemical studies on the role of the XPF-ERCC1 endonuclease in repairing damaged DNA replication forks
<p>The human XPF (ERCC4) and ERCC1 proteins form a heterodimeric endonuclease that plays a critical role in maintaining genome stability. Mutations in the XPF gene cause several heritable disorders including Fanconi anemia (FA). This highlights the importance of DNA repair processes controlled...
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| Format: | Thesis |
| Language: | English |
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2015
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