Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis

A prerequisite for protein synthesis is the transcription of ribosomal rRNA genes by RNA polymerase I (Pol I), which controls ribosome biogenesis. UBF (upstream binding factor) is one of the main Pol I transcription factors located in the nucleolus that activates rRNA gene transcription. E2F7 is an...

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Bibliographic Details
Main Authors: Coutts, A, Munro, S, La Thangue, N
Format: Journal article
Language:English
Published: Nature Publishing Group 2018