Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis
A prerequisite for protein synthesis is the transcription of ribosomal rRNA genes by RNA polymerase I (Pol I), which controls ribosome biogenesis. UBF (upstream binding factor) is one of the main Pol I transcription factors located in the nucleolus that activates rRNA gene transcription. E2F7 is an...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2018
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