Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase

Vacuolar-type ATPases (V-ATPases) are ATP-powered proton pumps involved in processes such as endocytosis, lysosomal degradation, secondary transport, TOR signalling, and osteoclast and kidney function. ATP hydrolysis in the soluble catalytic V1 region drives proton translocation through the membrane...

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Bibliographic Details
Main Authors: Mazhab-Jafari, M, Rohou, A, Schmidt, C, Bueler, S, Benlekbir, S, Robinson, C, Rubinstein, J
Format: Journal article
Language:English
Published: Springer Nature 2016