An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6.

Interleukin-6 (IL-6) is an important modulator of inflammation and immunity whose dysregulation is associated with a number of disease states. There is evidence of significant heritability in inter-individual variation in IL6 gene expression but the genetic variants responsible for this remain to be...

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Những tác giả chính: Fairfax, B, Vannberg, F, Radhakrishnan, J, Hakonarson, H, Keating, B, Hill, A, Knight, J
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Oxford University Press 2010