Investigation of the novel mTOR inhibitor AZD2014 in neuronal ischemia

<p><strong>Introduction:</strong> Hamartin, a component of the tuberous sclerosis complex (TSC) that actively inhibits the mammalian target of rapamycin (mTOR), may mediate the endogenous resistance of Cornu Ammonis 3 (CA3) hippocampal neurons following global cerebral ischemia. Ph...

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Bibliographic Details
Main Authors: Hadley, G, Beard, D, Alexopoulou, Z, Sutherland, B, Buchan, A
Format: Journal article
Language:English
Published: Elsevier 2019